The Office of Science and Engineering Laboratories’ Division of Solid and Fluid Mechanics (OSEL/DSFM) is leading an international effort to develop guidelines and provide a publicly-accessible repository of experimental data to make computational fluid dynamic (CFD) more effective for evaluating the safety of medical products by industry and FDA. CFD methods for describing flow patterns and fluid forces are increasingly being used in the development and premarket and postmarket evaluations of blood-contacting medical devices. However, this technology has limited usefulness due to the lack of reliable standardized techniques for assessing the validity and limitations of CFD simulations, and their predictions of blood damage. This project will make the necessary data and standards available for the use of this important tool.ON TRACKNOT YET STARTEDA. Update publicly-accessible data repository (<a href=https://fdacfd.nci.nih.gov target=”_blank”> https://fdacfd.nci.nih.gov</a>) with publications and reports on benchmark fluid flow patterns for future computational fluid dynamic (CFD) studies that will be submitted to CDRH4/30/2012Completed4/5/2012B. Provide technical input to the draft American Society of Mechanical Engineers (ASME) standard “Verification and validation for computational modeling of medical devices”5/30/2012Completed5/5/2012C. Complete study of Blood Pump Model11/30/2012Delayedsub1. Complete blood damage protocol for inter-laboratory testing4/30/2012Completed4/30/2012sub2. Complete quantitative flow visualization protocol for inter-laboratory testing5/30/2012Completed5/29/2012sub3. Complete blood damage inter-laboratory testing11/30/2012Delayedsub4. Complete quantitative flow visualization inter-laboratory testing11/30/2012DelayedD. Complete study of Nozzle Model12/31/2012Delayedsub1. Complete assessment of CFD performance in simulations of FDA’s first computational inter-laboratory study3/31/2012Completed3/30/2012sub2. Complete analysis of inter-laboratory blood damage testing8/31/2012Completed8/31/2012sub3. Submit journal article on inter-laboratory CFD studies with sudden contraction at inlet12/31/2012Delayedhttp://www.fda.gov/AboutFDA/Transparency/track/ucm203038.htmFDA-TRACK CDRH Dashboard਍††਍਍਍਍਍਍਍