Initiate development of a chemical evaluation and risk estimation system for pre- and post-market review of food ingredients. The system will enable FDA to fully leverage available data through modern computational and predictive methods for pre-market review as well as post-market monitoring of food ingredients and packaging materials. ON TRACK ON TRACK A. Develop Structure Editor 1/31/2010 <i>(3/31/2011)</i> <i>(6/15/2011)</i> Completed 5/27/2011 B. Establish list of requirements for CERES 3/30/2010 Completed 2/26/2010 C. Gentox computational tox models 3/30/2010 Completed 3/30/2010 D. Develop high level architecture 6/20/2010 Completed 6/20/2010 E. Carcinogenicity Model developed 7/31/2010 Completed 6/30/2010 F. System Requirements external review completed 8/31/2010 Completed 8/1/2010 G. ToxML and PAFA data migrated 9/30/2010 Completed 10/25/2010 H. Chromosome Aberration Model developed and in testing 9/30/2010 Completed 10/25/2010 I. Carcinogenicity and Chromosome Aberration Model Validated 11/30/2010 Completed 12/23/2010 J. Stand up initial operational version of CERES 12/31/2010 Completed 12/23/2010 K. Completed initial testing 2/28/2011 Completed 2/25/2011 L. Apply models to all authorized food chemicals 3/31/2011 <i>(9/30/2011)</i> <i>(1/31/2013)</i> On Track M. Start operational testing 4/1/2011 Completed 3/15/2011 N. Model validation of repro-dev models scheduled for completion 7/31/2011 Completed 6/15/2011 O. End operational testing 3/31/2012 <i>(9/30/2012)</i> Completed 9/30/2012 P. Release of CERES Version 1, which is not a fully automated version 3/31/2012 <i>(9/30/2012)</i> Completed 9/30/2012 Q. Release of CERES Version 2, which is a fully automated risk assessment tool 3/31/2013 <i>(1/31/2014)</i> <i>(8/30/2013)</i> Not Yet Started R. Complete Enterprise Performance Life Cycle testing 1/31/2014 Not Yet Started S. Receive authority to operate from Chief Information Officer 4/30/2014 Not Yet Started The dates in italics under the milestone due dates are modified milestone due dates which had to be updated due to real-time delays. The milestone status reflects the revised dates. http://www.fda.gov/AboutFDA/Transparency/track/ucm206221.htmFDA-TRACK CFSAN Dashboard ਍††਍਍਍਍਍਍਍