1 Introduction
    1.1 Objective
2 Overview of the Registration Process
    2.1 Apply for a Test
    2.2 Test Account Setup
    2.3 Send a Test Submission
    2.4 Apply for a Production System Account
    2.5 Production System Account Setup and Approval
    2.6 Send Submissions to the Production System
3 Preparatory Activities
    3.1 Submit Letter of Non-Repudiation Agreement
    3.2 Obtain Digital Certificate
    3.3 Understand Submission Guidelines
    3.4 Naming Conventions
    3.5 Determine Submission Method
    3.6 Connection Requirements
    3.7 Help and Information
4 FDA ESG Web Interface Electronic Submissions
    4.1 Apply for a Test Account
    4.2 Test Account Setup and Approval
    4.3 Send a Test Submission
    4.4 Apply for a Production System Account
    4.5 Production System Account Setup and Approval
    4.6 Send Submissions to the Production System
    4.7 Sending Large (> 7.5 GB) Submissions
    4.8 Tracking Submissions
5 AS2 Gateway-to-Gateway Electronic Submissions
    5.1 Apply for a Test Account
    5.2 Test Account Setup and Approval
    5.3 Send a Test Submission
    5.4 Apply for a Production System Account
    5.5 Production System Account Setup and Approval
    5.6 Send Submissions to the Production System
    5.7 Sending Large (> 7.5 GB) Submissions
    5.8 Common AS2 Errors
6 References/Resources
    Appendix A. Troubleshooting the FDA ESG Web Interface
    Appendix B. Creating Tar Files and Compressing Files for Submission
    Appendix C. Digital Certificates
    Appendix D. Java Runtime Edition
    Appendix E. Glossary of Terms
    Appendix F. Acronyms
    Appendix G. AS2 Header Attributes
    Appendix H. Sample Letters of Non-Repudiation Agreement
    Appendix I. EDIFACT Message Structure
    Appendix J. Digital Signatures
    Appendix K. AS2_Routing_IDs