FDA Poisonous Plant Database
AUTHOR(S): Rodriguez, E.; Reynolds, G. W.; Thompson, J. A.
TITLE: Potent contact allergen in the rubber plant guayule (Parthenium argentatum).
YEAR: 1981 CITATION: Science, 211(4489), 1444-1445 [English]
FDA #: F18472
ABSTRACT: Chemical and dermatotoxicological investigations of the natural and processed resin of the Mexican rubber plant, guayule (Parthenium argentatum), has established the presence of a sesquiterpene cinnamic acid ester (guayulin A) that is a potent elicitor of allergic contact dermatitis in experimental animals. The guayule contact allergen is comparable to the poison ivy skin allergens as an elicitor of dermatitis in sensitized guinea pigs.
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