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U.S. Department of Health and Human Services

PhishPharm - Detail
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Title:  Drug uptake and disposition in fish: An autoradiographic study with dihydrostreptomycin in the rainbow trout.
 
Authors:  Czerwinska K, Sunk RB, Sognen E
 
Drug:  Dihydrostreptomycin
 
Fish species:  Trout, rainbow
 
Date:  1990
 
Sample:  brain+spinal cord
 
Ave Weight (gm):  30
 
Ave Water temp (°C):  6
 
Water:  Freshwater
 
Dosage:  0.125 mg sd
 
Route:  IM
 
Comments:  Long retention time at injection site muscle site of highest radioactivity, but not in other muscle sites. DHS eliminated by excretion through the gills, kidney, liver, and biliary. After 42 hr activity only seen in intestinal tract at low levels (3H)DHS.
 
Citation:  Acta Pharmaceutica Nordica 2:6:377-386
 
Link:  http://www.cabdirect.org/abstracts/19912216788.html  Opens a new window
 
Genus Species:  Oncorhynchus mykiss
 
Drug Class:  Antibiotic-Aminoglycoside
 
Wt gm-detail:  30 g
 
Water temp (°C)-detail:  5.5-6 C
 
Dosage-detail:  0.125 mg sd
 
Method:  Rad/Whole body Autoradiography
 
Authors-red:  Czerwinska K, Sunk RB, Sognen E
 
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