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U.S. Department of Health and Human Services

PhishPharm - Detail

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Title:  Drug uptake and disposition in fish: An autoradiographic study with dihydrostreptomycin in the rainbow trout.
Authors:  Czerwinska K, Sunk RB, Sognen E
Drug:  Dihydrostreptomycin
Fish species:  Trout, rainbow
Date:  1990
Sample:  liver
Ave Weight (gm):  30
Ave Water temp (°C):  6
Water:  Freshwater
Dosage:  0.125 mg sd
Route:  IM
Comments:  Long retention time at injection site muscle site of highest radioactivity, but not in other muscle sites. DHS eliminated by excretion through the gills, kidney, liver, and biliary. After 42 hr activity only seen in intestinal tract at low levels (3H)DHS.
Citation:  Acta Pharmaceutica Nordica 2:6:377-386
Link:  http://www.cabdirect.org/abstracts/19912216788.html  Opens a new window
Genus Species:  Oncorhynchus mykiss
Drug Class:  Antibiotic-Aminoglycoside
Wt gm-detail:  30 g
Water temp (°C)-detail:  5.5-6 C
Dosage-detail:  0.125 mg sd
Method:  Rad/Whole body Autoradiography
Authors-red:  Czerwinska K, Sunk RB, Sognen E