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U.S. Department of Health and Human Services

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Title:  Drug uptake and disposition in fish: An autoradiographic study with dihydrostreptomycin in the rainbow trout.
 
Authors:  Czerwinska K, Sunk RB, Sognen E
 
Drug:  Dihydrostreptomycin
 
Fish species:  Trout, rainbow
 
Date:  1990
 
Sample:  muscle
 
Ave Weight (gm):  100
 
Ave Water temp (°C):  6
 
Water:  Freshwater
 
Dosage:  10 mg sd
 
Route:  PO
 
Comments:  At 6 hr - high activity in intestine and some in blood, liver, kidney, gills and eyes but not muscle. By 24 h - increased activity in blood, liver and kidney and base of dorsal fin, highest activity in GI. 48 hr-72 hr most in distal intestine. At 7 days kidney and liver were still active with GI still highest, continuing through 3 wks (3H)DHS.
 
Citation:  Acta Pharmaceutica Nordica 2:6:377-386
 
Link:  http://www.cabdirect.org/abstracts/19912216788.html  Opens a new window
 
Genus Species:  Oncorhynchus mykiss
 
Drug Class:  Antibiotic-Aminoglycoside
 
Wt gm-detail:  100 g
 
Water temp (°C)-detail:  5.5-6 C
 
Dosage-detail:  10 mg sd
 
Method:  Rad/Whole body Autoradiography
 
Authors-red:  Czerwinska K, Sunk RB, Sognen E
 
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