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U.S. Department of Health and Human Services

PhishPharm - Detail

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Title:  Plasma and tissue levels of trimethoprim in the Rainbow trout, Salmo gairdneri, after absorption from fresh and salt water.
Authors:  Bergsjo T, Sognen E
Drug:  Trimethoprim
Fish species:  Trout, rainbow
Date:  1980
Sample:  blood, plasma
Ave Weight (gm):  120
Ave Water temp (°C):  9
Water:  Freshwater
Dosage:  75 mg/l 5-48 hr sd
Route:  BATH
Comments:  Plasma concentrations never reached 1 ug/ml. Saltwater adapted fish had highest levels of drug, followed by those not adapted, and least in freshwater dosed fish.
Citation:  Acta Veterinaria Scandinavia 21:18-25
Link:  http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=7386327  Opens a new window
Genus Species:  Oncorhynchus mykiss
Drug Class:  Antibiotic-Sulfa
t1/2-detail:  Not Specified
Wt gm-detail:  120 g
Water temp (°C)-detail:  9 C
Dosage-detail:  75 mg/l for 5-48 hr sd
Method:  Micro
Authors-red:  Bergsjo T, Sognen E