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U.S. Department of Health and Human Services

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Title:  Analysis of erythromycin A and its metabolites in incurred and fortified salmon by LC/ED and LC/ESI-MS.
 
Authors:  Billedeau SM, Heinze TM, Siitonen PH, Reimschuessel R, Gieseker C, Moffitt CM
 
Drug:  Erythromycin
 
Fish species:  Salmon, Atlantic
 
Date:  2003
 
Sample:  muscle
 
Ave Weight (gm):  1000
 
Ave Water temp (°C):  13
 
Water:  Freshwater
 
Dosage:  20 mg/kg, 2 doses, 24 hrs apart
 
Route:  PO
 
Comments:  Residue = 1200 ppb 4 hrs after the last dose.
 
Metabolites:  N-demethyl erythromycin and anhydro-erythromycin
 
Citation:  American Chemical Society, National 225th Meeting-abstract
 
Link:  http://oasys2.confex.com/acs/225nm/techprogram/P613476.HTM  Opens a new window
 
Genus Species:  Salmo salar
 
Drug Class:  Antibiotic-Macrolide
 
Wt gm-detail:  1000 +/-300
 
Water temp (°C)-detail:  12-14 C
 
Dosage-detail:  20 mg/kg, 2 doses, 24 hrs apart
 
Method:  LC/ED, LC/ESI, MS
 
Authors-red:  Billedeau SM, Heinze TM, Siitonen PH, Reimschuessel R, Gieseker C, Moffitt CM
 
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