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U.S. Department of Health and Human Services

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Title:  Tissue levels of oxolinic acid after oral and intravascular administration to freshwater and seawater rainbow trout.
 
Authors:  Ishida N
 
Drug:  Oxolinic acid
 
Fish species:  Trout, rainbow
 
Date:  1992
 
Sample:  kidney
 
Ave Weight (gm):  472
 
Ave Water temp (°C):  16
 
Water:  Saltwater
 
Dosage:  40 mg/kg
 
Route:  PO
 
Comments:  Tissue concentrations of the drug peaked at 48h and were detectable for at least 244h vs undetectable by 72h in saltwater group. Glucuronide metabolites in bile of both salt and freshwater groups. Residue 24h=3.1, 72h=nd ug/gm.
 
Citation:  Aquaculture 102:9-15
 
Link:  http://dx.doi.org/10.1016/0044-8486(92)90284-R  Opens a new window
 
Genus Species:  Oncorhynchus mykiss
 
Drug Class:  Antibiotic-Quinolone
 
Wt gm-detail:  472 g
 
Water temp (°C)-detail:  16 C
 
Dosage-detail:  40 mg/kg
 
Method:  HPLC
 
Authors-red:  Ishida N
 
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