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U.S. Department of Health and Human Services

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Title:  Pharmacokinetics and bioavailability of flumequine and oxolinic acid after various routes of administration to Atlantic salmon in seawater.
Authors:  Rogstad A, Ellingsen OF, Syvertsen C
Drug:  Oxolinic acid
Fish species:  Salmon, Atlantic
Date:  1993
t1/2-hr:  72
est:  est
Sample:  muscle
Ave Weight (gm):  425
Ave Water temp (°C):  5
Water:  Saltwater
Dosage:  25 mg/kg sd
Route:  PO
Comments:  Apoxolon Aqualets 5 g/kg. Salinity 30 ppt. AUC= 286 ug h/g. Residues ug/g 4h=0, 8h=0.3, 12h=1.9, 24h=5.7, 48h=4.0, 72h=2.3, 96h=1.6.
Citation:  Aquaculture 110:207-220
Link:  http://www.sciencedirect.com/science/article/pii/004484869390369A  Opens a new window
Genus Species:  Salmo salar
Drug Class:  Antibiotic-Quinolone
t1/2-detail:  72 h est
Wt gm-detail:  425 g
Water temp (°C)-detail:  5+/-0.2 C
Dosage-detail:  25 mg/kg sd
Method:  HPLC
Authors-red:  Rogstad A, Ellingsen OF, Syvertsen C