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U.S. Department of Health and Human Services

PhishPharm - Detail
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Title:  Pharmacokinetics and bioavailability of flumequine and oxolinic acid after various routes of administration to Atlantic salmon in seawater.
 
Authors:  Rogstad A, Ellingsen OF, Syvertsen C
 
Drug:  Oxolinic acid
 
Fish species:  Salmon, Atlantic
 
Date:  1993
 
t1/2-hr:  90
 
est:  est
 
Sample:  blood, plasma
 
Ave Weight (gm):  425
 
Ave Water temp (°C):  5
 
Water:  Saltwater
 
Dosage:  50 mg/kg sd
 
Route:  PO
 
Comments:  Bioavailability=25% AUC = 58.9 ug h/ml. C-max=1.17 at 24h. Salinity 30 ppt.
 
Citation:  Aquaculture 110:207-220
 
Link:  http://www.sciencedirect.com/science/article/pii/004484869390369A  Opens a new window
 
Genus Species:  Salmo salar
 
Drug Class:  Antibiotic-Quinolone
 
t1/2-detail:  90 h est
 
Wt gm-detail:  425 g
 
Water temp (°C)-detail:  5+/-0.2 C
 
Dosage-detail:  50 mg/kg sd
 
Method:  HPLC
 
Authors-red:  Rogstad A, Ellingsen OF, Syvertsen C
 
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