Quick Links: Skip to main page content Skip to Search Skip to Topics Menu Skip to Common Links
  • Decrease font size
  • Return font size to normal
  • Increase font size
U.S. Department of Health and Human Services

PhishPharm - Detail
  • Print
  • Share
  • E-mail
-
 
Title:  Pharmacokinetics, tissue distribution, and metabolism of nitrofurantoin in the channel catfish (Ictalurus punctatus).
 
Authors:  Stehly GR, Plakas SM (1993)
 
Drug:  Nitrofurantoin
 
Fish species:  Catfish, channel
 
Date:  1993
 
t1/2-hr:  1
 
Sample:  blood, plasma
 
Ave Weight (gm):  700
 
Ave Water temp (°C):  25
 
Water:  Freshwater
 
Dosage:  10 mg/kg sd
 
Route:  IV
 
Comments:  14C-Nitrofurantoin. Catheterized fish. AUC 16.2 ug/h/ml.
 
Cl:  0.62 L/kg/h
 
Vd:  0.33 L/Kg
 
Metabolites:  5 metabolites
 
Citation:  Aquaculture 113:1-10
 
Link:  http://dx.doi.org/10.1016/0044-8486(93)90335-V  Opens a new window
 
Genus Species:  Ictalurus punctatus
 
Drug Class:  Antibiotic-Furan
 
t1/2-detail:  23 min
 
Wt gm-detail:  0.4-1.0 kg
 
Water temp (°C)-detail:  25 C
 
Dosage-detail:  10 mg/kg sd
 
Method:  HPLC-Rad
 
Authors-red:  Stehly GR, Plakas SM (1993)
 
-
-