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U.S. Department of Health and Human Services

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Title:  Temperature-dependent absorption and elimination of flumequine in rainbow trout (Oncorhynchus mykiss Walbaum) in fresh water.
 
Authors:  Sohlberg S, Aulie A, Soli NE
 
Drug:  Flumequine
 
Fish species:  Trout, rainbow
 
Date:  1994
 
t1/2-hr:  285
 
Sample:  blood, plasma
 
Ave Weight (gm):  498
 
Ave Water temp (°C):  13
 
Water:  Freshwater
 
Dosage:  5 mg/kg sd
 
Route:  PO
 
Comments:  Catheterized fish. Residues 2h=1.4, 4h=1.5, 8h=1.7, 12h=1.9, 24h=1.9, 35h=1.8, 49h=1.8, 74h= 1.6, 98h=1.3, 123h=1.4, 144h=1.2, 194h=1.2, 241h=1.1, 337h=0.9, 505h=0.4. ug/ml. t 1/2 alpha=16h, beta=285h.
 
Citation:  Aquaculture 119:1-10
 
Link:  http://dx.doi.org/10.1016/0044-8486(94)90439-1  Opens a new window
 
Genus Species:  Oncorhynchus mykiss
 
Drug Class:  Antibiotic-Quinolone
 
t1/2-detail:  alpha=16h, beta=285h.
 
Wt gm-detail:  499+/-133 g
 
Water temp (°C)-detail:  13+/-1 C
 
Dosage-detail:  5 mg/kg sd
 
Method:  HPLC
 
Authors-red:  Sohlberg S, Aulie A, Soli NE
 
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