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U.S. Department of Health and Human Services

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Title:  Temperature-dependent absorption and elimination of flumequine in rainbow trout (Oncorhynchus mykiss Walbaum) in fresh water.
 
Authors:  Sohlberg S, Aulie A, Soli NE
 
Drug:  Flumequine
 
Fish species:  Trout, rainbow
 
Date:  1994
 
t1/2-hr:  736
 
Sample:  blood, plasma
 
Ave Weight (gm):  498
 
Ave Water temp (°C):  3
 
Water:  Freshwater
 
Dosage:  5 mg/kg sd
 
Route:  PO
 
Comments:  Catheterized fish. Residues 2h=0.3, 6h=0.5, 9h=0.4, 23h=1.0, 35h=0.9, 49h=1.1, 73h=1.0, 120h=0.92, 193h=0.8, 290h=0.6, 439h=0.6, 771h=0.4 ug/ml. T1/2 alpha=38h, beta = 736h.
 
Citation:  Aquaculture 119:1-10
 
Link:  http://dx.doi.org/10.1016/0044-8486(94)90439-1  Opens a new window
 
Genus Species:  Oncorhynchus mykiss
 
Drug Class:  Antibiotic-Quinolone
 
t1/2-detail:  alpha=38h, beta = 736h.
 
Wt gm-detail:  499+/-133 g
 
Water temp (°C)-detail:  3+/-1 C
 
Dosage-detail:  5 mg/kg sd
 
Method:  HPLC
 
Authors-red:  Sohlberg S, Aulie A, Soli NE
 
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