Quick Links: Skip to main page content Skip to Search Skip to Topics Menu Skip to Common Links
  • Decrease font size
  • Return font size to normal
  • Increase font size
U.S. Department of Health and Human Services

PhishPharm - Detail
  • Print
  • Share
  • E-mail
-
 
Title:  Distribution and elimination of [14C]sarafloxacin hydrochloride from tissues of juvenile channel catfish (Ictalurus punctatus).
 
Authors:  Gingerich WH, Meinertz JR, Dawson VK, Gofus JE, Delaney LJ, Bunnell PR
 
Drug:  Sarafloxacin
 
Fish species:  Catfish, channel
 
Date:  1995
 
t1/2-hr:  9
 
Sample:  muscle
 
Ave Weight (gm):  50
 
Ave Water temp (°C):  25
 
Water:  Freshwater
 
Dosage:  10 mg/kg 5 d
 
Route:  PO
 
Comments:  Highest mean concentration of parent-equivalent material found 12 h after last dose, Half life determined by radioactive counting=9.33 h, by fluorometric method t 1/2 = 8.89 h. The gamma phase t 1/2 = 185 h. Sarafloxacin (C14). oral gavage. Residues (ng/g) 3h=1711, 12 hr = 2268, 48 h = 359. 240 h=8.1.
 
Citation:  Aquaculture 131:23-36
 
Link:  http://dx.doi.org/10.1016/0044-8486(94)00362-R  Opens a new window
 
Genus Species:  Ictalurus punctatus
 
Drug Class:  Antibiotic-Quinolone
 
t1/2-detail:  8.9 h
 
Wt gm-detail:  38.4-62.0 g
 
Water temp (°C)-detail:  24.8+/-0.5 C
 
Dosage-detail:  9.82 mg/kg+/-0.71
 
Method:  HPLC-Rad
 
Authors-red:  Gingerich WH, Meinertz JR, Dawson VK, Gofus JE, Delaney LJ, Bunnell PR
 
-
-