Quick Links: Skip to main page content Skip to Search Skip to Topics Menu Skip to Common Links
  • Decrease font size
  • Return font size to normal
  • Increase font size
U.S. Department of Health and Human Services

PhishPharm - Detail
  • Print
  • Share
  • E-mail
-
 
Title:  Multiple-dose pharmacokinetic study of Romet 30 in Atlantic salmon (Salmo salar) and in vitro antibacterial activity against Aeromonas salmonicida.
 
Authors:  Samuelsen OB, Pursell L, Smith P, Ervik A
 
Drug:  Ormetoprim
 
Fish species:  Salmon, Atlantic
 
Date:  1997
 
t1/2-hr:  63
 
Sample:  blood, plasma
 
Ave Weight (gm):  525
 
Ave Water temp (°C):  10
 
Water:  Saltwater
 
Dosage:  5/25 OMP/SDM mg/kg/d 5d
 
Route:  PO
 
Comments:  Drug fed to fish after given multiple doses of Romet-30; OMP accumulation may be related to its binding to specific proteins including possibly those involved in hematopoiesis in the head kidney.
 
Protein binding:  yes
 
Citation:  Aquaculture 152:13-24
 
Link:  http://dx.doi.org/10.1016/S0044-8486(96)01508-6  Opens a new window
 
Genus Species:  Salmo salar
 
Drug Class:  Antibiotic-Sulfa
 
t1/2-detail:  63h
 
Wt gm-detail:  450-600g
 
Water temp (°C)-detail:  10.0+/-0.5C
 
Dosage-detail:  5/25 OMP/SDM mg/kg/d 5d
 
Method:  HPLC
 
Authors-red:  Samuelsen OB, Pursell L, Smith P, Ervik A
 
-
-