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U.S. Department of Health and Human Services

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Title:  Single dose pharmacokinetic study of flumequine after intravenous, intraperitoneal and oral administration to Atlantic halibut (Hippoglossus hippoglossus) held in seawater at 9oC.
 
Authors:  Samuelsen OB, Ervik A (1997)
 
Drug:  Flumequine
 
Fish species:  Halibut, Atlantic
 
Date:  1997
 
t1/2-hr:  48
 
est:  est
 
Sample:  blood, plasma
 
Ave Weight (gm):  2000
 
Ave Water temp (°C):  9
 
Water:  Saltwater
 
Dosage:  25 mg/kg sd
 
Route:  PO
 
Comments:  t 1/2 estimated from graph. Bioavailability 31%. Residue peak at 24 h = 3.25, 48 h= 1.22, 96 h= 0.22, 240 h= 0.11 ug/ml.
 
Citation:  Aquaculture 158:215-227
 
Link:  http://dx.doi.org/10.1016/S0044-8486(97)00190-7  Opens a new window
 
Genus Species:  Hippoglossus hippoglossus
 
Drug Class:  Antibiotic-Quinolone
 
t1/2-detail:  48 h est
 
Wt gm-detail:  1.5- 2.5 kg
 
Water temp (°C)-detail:  9 C
 
Dosage-detail:  25 mg/kg sd
 
Method:  HPLC
 
Authors-red:  Samuelsen OB, Ervik A (1997)
 
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