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Title:
Single dose pharmacokinetic study of flumequine after intravenous, intraperitoneal and oral administration to Atlantic halibut (Hippoglossus hippoglossus) held in seawater at 9oC.
Authors:
Samuelsen OB, Ervik A (1997)
Drug:
Flumequine
Fish species:
Halibut, Atlantic
Date:
1997
t1/2-hr:
48
est:
est
Sample:
blood, plasma
Ave Weight (gm):
2000
Ave Water temp (°C):
9
Water:
Saltwater
Dosage:
25 mg/kg sd
Route:
PO
Comments:
t 1/2 estimated from graph. Bioavailability 31%. Residue peak at 24 h = 3.25, 48 h= 1.22, 96 h= 0.22, 240 h= 0.11 ug/ml.
Citation:
Aquaculture 158:215-227
Link:
http://dx.doi.org/10.1016/S0044-8486(97)00190-7
Genus Species:
Hippoglossus hippoglossus
Drug Class:
Antibiotic-Quinolone
t1/2-detail:
48 h est
Wt gm-detail:
1.5- 2.5 kg
Water temp (°C)-detail:
9 C
Dosage-detail:
25 mg/kg sd
Method:
HPLC
Authors-red:
Samuelsen OB, Ervik A (1997)
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