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U.S. Department of Health and Human Services

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Title:  Bioaccumulation of trimethoprim, sulfamethoxazole and N-acetyl-sulfamethoxazole in Artemia nauplii and residual kinetics in seabass larvae after repeated oral dosing of medicated nauplii.
 
Authors:  Touraki M, Niopas I, Kastritsis C
 
Drug:  Sulfamethoxazole
 
Fish species:  Seabass, European
 
Date:  1999
 
t1/2-hr:  26
 
Sample:  whole body
 
Ave Weight (gm):  0.11
 
Ave Water temp (°C):  20
 
Water:  Saltwater
 
Dosage:  88.5 mg/kg via medicated nauplii 5 d
 
Route:  PO
 
Comments:  Residues: All 3 drugs (sulfamethoxazole, N4-A SMX, TMP) detected 100 h post treatment
 
Cl:  0.75+/-0.05 g/h
 
Citation:  Aquaculture 175:15-30
 
Link:  http://dx.doi.org/10.1016/S0044-8486(99)00036-8  Opens a new window
 
Genus Species:  Dicentrarchus labrax
 
Drug Class:  Antibiotic-Sulfa
 
t1/2-detail:  25.62+/-2.19 h
 
Wt gm-detail:  0.1-0.12 g
 
Water temp (°C)-detail:  20 C
 
Dosage-detail:  88.5 mg/kg via medicated nauplii for 5 d
 
Method:  HPLC
 
Authors-red:  Touraki M, Niopas I, Kastritsis C
 
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