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Title:
Dosage regime experiments with oxolinic acid and flumequine in Atlantic salmon (Salmo salar L) held in sea water.
Authors:
Ellingsen OF, Midttun B, Rogstad A, Syversten C, Samuelsen OB
Drug:
Oxolinic acid
Fish species:
Salmon, Atlantic
Date:
2002
Sample:
liver
Ave Weight (gm):
2000
Ave Water temp (°C):
20
Water:
Saltwater
Dosage:
158 mg/kg on d 1,2,4,6
Route:
PO
Comments:
Dosing done on farm with outbreak of furnculosis. Fed Apoxolon Akvaletter Vet 5 g/kg. Good distribution in plasma, muscle and liver with concentration in the 1.7-29.2 ug/ml range. Flumequine conc were 2-9 times higher than oxolinic acid.
Citation:
Aquaculture 209:19-34
Link:
http://dx.doi.org/10.1016/S0044-8486(01)00804-3
Genus Species:
Salmo salar
Drug Class:
Antibiotic-Quinolone
Wt gm-detail:
2000 g
Water temp (°C)-detail:
17-22 C
Dosage-detail:
158 mg/kg fish fed d 1,2,4,6
Method:
HPLC
Authors-red:
Ellingsen OF, Midttun B, Rogstad A, Syversten C, Samuelsen OB
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