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Title:
A comparison of oxolinic acid concentrations in farmed and laboratory held rainbow trout (Oncorhynchus mykiss) following oral therapy.
Authors:
Coyne R, Samuelsen O, Kongshaug H, Andersen K, Dalsgaard I, Smith P, Bergh O.
Drug:
Oxolinic acid
Fish species:
Trout, rainbow
Date:
2004
Sample:
blood, plasma
Ave Weight (gm):
165
Ave Water temp (°C):
12
Water:
Saltwater
Dosage:
50mg/kg 6 d*
Route:
PO
Comments:
Lab fish Healthy: Medicated feed 5g/kg fed at 1% body wt on days 1,2,3,5,7,9. Study compared healthy laboratory fish with farm fish during an outbreak of Vibrio. Residues, mg/l, 24 hr p feeding Lab fish=0.133 (<0.005-0.266) 80th %=0.09, Coef Var 51%, Heathy farm=0.156 (<0.005-0.602) 80%=0.05, Coef Var 97% Not statistically different. 22 of 29 moribund and 6 of 10 dead fish had no essentially residues, and were not feeding..
Citation:
Aquaculture 239:1-13
Link:
http://dx.doi.org/10.1016/j.aquaculture.2003.11.034
Genus Species:
Oncorhynchus mykiss
Drug Class:
Antibiotic-Quinolone
Wt gm-detail:
165+/-33 g
Water temp (°C)-detail:
12 C
Dosage-detail:
Medicated feed 50mg/kg for 6 d*
Method:
HPLC
Authors-red:
Coyne R, Samuelsen O, Kongshaug H, Andersen K, Dalsgaard I, Smith P, Bergh O.
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