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Title:
Oxytetracycline residues in cultivated marine shrimp (Litopenaeus vannamei Boone, 1931) (Crustacea, Decapoda) submitted to antibiotic treatment.
Authors:
Nogueira-Lima AC, Gesteira TCV, Mafezoli J
Drug:
Oxytetracycline
Fish species:
Shrimp, whiteleg
Date:
2006
t1/2-hr:
36
est:
est
Sample:
muscle
Ave Weight (gm):
5
Ave Water temp (°C):
27
Water:
Saltwater
Dosage:
200 mg/kg 14 d
Route:
PO
Comments:
Laboratory experiment. Initial wt 5 g, near 6 g at end. Salinity 34.4 ppt. OTC consumption 17.61% higher than in pond experiment. Avg Cmax=17.21 ug/g after 7d, d14=11.98. t1/2-hr extrapolated from curve. Ave Conc Depletion d1=6 ug/g, d2=3.9 d17=0.17 ug/g. Slower depletion 4d to end of study. Tissues were called "abdominal tissue" - presumably muscle.
Citation:
Aquaculture 254:748-758
Dep-time:
25 d
Link:
http://dx.doi.org/10.1016/j.aquaculture.2005.11.021
Genus Species:
Litopenaeus vannamei
Drug Class:
Antibiotic-Tetracycline
t1/2-detail:
36 h est
Wt gm-detail:
5.08+/-0.63g
Water temp (°C)-detail:
26.8+/-0.3 C
Dosage-detail:
4 gm/kg in feed 14 d
Method:
HPLC
Authors-red:
Nogueira-Lima AC, Gesteira TCV, Mafezoli J
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