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U.S. Department of Health and Human Services

PhishPharm - Detail
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Title:  Tissue distribution and elimination of norfloxacin in Japanese sea perch (Lateolabras japonicus) and black sea bream (Sparus macrocephalus) following multi-oral administration.
 
Authors:  Wang Q, Liu Q, Li J, Wang Q
 
Drug:  Norfloxacin
 
Fish species:  Seabream, blackhead
 
Date:  2008
 
t1/2-hr:  93
 
Sample:  kidney
 
Ave Weight (gm):  165
 
Ave Water temp (°C):  15.7
 
Water:  Saltwater
 
Dosage:  30mg/kg/d, 5d
 
Route:  PO
 
Comments:  Seawater -30ppt. Mean drug concentration = 20.06ug/g 1d post-dosing.
 
Citation:  Aquaculture 278:1-4
 
Link:  http://dx.doi.org/10.1016/j.aquaculture.2008.03.021  Opens a new window
 
Genus Species:  Acanthopagrus schlegelii schlegelii
 
Drug Class:  Antibiotic-Quinolone
 
t1/2-detail:  3.87d
 
Wt gm-detail:  150-180g
 
Water temp (°C)-detail:  15.7+/-1.0
 
Dosage-detail:  30mg/kg/d for 5d
 
Method:  HPLC-UV
 
Authors-red:  Wang Q, Liu Q, Li J, Wang Q
 
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