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U.S. Department of Health and Human Services

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Title:  Leaching, palatability and digestibility of oxytetracycline and oxolinic acid included in diets fed to seabass Dicentrarchus labrax L.
 
Authors:  Rigos G, Alexis M, Nengas I
 
Drug:  Oxolinic acid
 
Fish species:  Seabass, European
 
Date:  1999
 
Sample:  intestinal tract-feces
 
Ave Weight (gm):  350
 
Ave Water temp (°C):  24
 
Water:  Saltwater
 
Dosage:  30 mg/kg 3d
 
Route:  PO
 
Comments:  Drug well digested (94 +/-4.3% at 24 C) but poorly digested at 16 C (64 +/-1.2%) (1/3 drug in feces). Oil coated feeds leached more antimicrobial if topcoated (55.5% loss at 16 and 32% at 24C), vs when mixed in feeds (5% at 16, 10% at 24C).Palatability not affected by top coating.
 
Citation:  Aquaculture Research 30:841-841-847
 
Link:  http://www.blackwell-synergy.com/doi/abs/10.1046/j.1365-2109.1999.00410.x?journalCode=are  Opens a new window
 
Genus Species:  Dicentrarchus labrax
 
Drug Class:  Antibiotic-Quinolone
 
Wt gm-detail:  350 g
 
Water temp (°C)-detail:  24
 
Dosage-detail:  30 mg/kg 3d
 
Method:  HPLC
 
Authors-red:  Rigos G, Alexis M, Nengas I
 
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