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U.S. Department of Health and Human Services

PhishPharm - Detail

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Title:  Accumulation and depuration of microcystins (cyanobacteria hepatotoxins) in Tilapia rendalli (Cichlidae) under laboratory conditions.
 
Authors:  Soares RM, Magalhaes VF, Azevedo SM
 
Drug:  Microcystin
 
Fish species:  Tilapia, redbreast
 
Date:  2004
 
Sample:  liver
 
Ave Weight (gm):  0
 
Ave Water temp (°C):  24
 
Water:  Freshwater
 
Dosage:  2.2 ug/fish/d 42 d
 
Route:  PO
 
Comments:  Accumulation phase ug/g: 7d=0.5, 14d=1.0, 21d=1.25, 28d=0.25, 35d=0.5, 42d=1.5. Excretion via feces, Eliza cannot pick up metabolites so total accumulation is underestimated. Microcystis aeruginosa cells.. Toxic cells had been lysed.
 
Citation:  Aquatic Toxicology 18:1-10
 
Link:  http://dx.doi.org/10.1016/j.aquatox.2004.06.013  Opens a new window
 
Genus Species:  Tilapia rendalli
 
Drug Class:  Organic-Cyanotoxin
 
Wt gm-detail:  juveniles 5+/-1 cm long
 
Water temp (°C)-detail:  23.5+/-0.5 C
 
Dosage-detail:  toxic cells +food, MCYSTs 29.2 ug/fish/day 42 d
 
Method:  ELISA
 
Authors-red:  Soares RM, Magalhaes VF, Azevedo SM
 
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