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U.S. Department of Health and Human Services

PhishPharm - Detail

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Title:  Toxicokinetics of copper in rainbow trout.
 
Authors:  Carbonell G, Tarazona JV
 
Drug:  Copper
 
Fish species:  Trout, rainbow
 
Date:  1994
 
t1/2-hr:  3
 
Sample:  blood, plasma
 
Ave Weight (gm):  200
 
Ave Water temp (°C):  18
 
Water:  Freshwater
 
Dosage:  80 ug/kg sd
 
Route:  IV
 
Comments:  t 1/2 alpha = 7. 2 min. AUC = 108.6+/- 29. Volume of central compartment = 43 ml/ kg, volume of perpheral compartment = 135 ml/kg - similar to other author's reports.
 
Vc:  0.043 L/kg
 
Vd:  0.178 L/kg
 
Citation:  Aquatic Toxicology 29:213-221
 
Link:  http://dx.doi.org/10.1016/0166-445X(94)90069-8   Opens a new window
 
Genus Species:  Oncorhynchus mykiss
 
Drug Class:  Metal-Copper
 
t1/2-detail:  3.26+/-0.72 h
 
Wt gm-detail:  100-300 g
 
Water temp (°C)-detail:  18+/-1 C
 
Dosage-detail:  80 ug/kg sd
 
Method:  AAS
 
Authors-red:  Carbonell G, Tarazona JV
 
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