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U.S. Department of Health and Human Services

PhishPharm - Detail

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Title:  Comparative toxicokinetics of explosive compounds in Sheepshead minnows.
Authors:  Lotufo GR, Lydy MJ
Drug:  Hexahydro-1,3,5-Trinitro-1,3,5-triazine (RDX),
Fish species:  Minnow, sheepshead
Date:  2005
t1/2-hr:  8
Sample:  whole body
Ave Water temp (°C):  23
Water:  Saltwater
Dosage:  8.5 mg/L up to 6 h
Route:  BATH
Comments:  Ku-uptake (ml/g/h) = 0.15, Ke=0.09/h, BCF=N/A mg/g. No trend between elimination rate ahdn hydrophobicity among the chemicals studied (RDX and HMX slower than TNT and its metabolites.
Citation:  Archives of Environmental Contamination and Toxiciology
Link:  http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=16059748&query_hl=3  Opens a new window
Genus Species:  Cyprinodon variegatus variegatus
Drug Class:  Organic-Hydrocarbon
t1/2-detail:  7;9 h
Wt gm-detail:  12 wk juvenile
Water temp (°C)-detail:  23 C
Dosage-detail:  8.5 mg/L up to 6 h
Method:  HPLC
Authors-red:  Lotufo GR, Lydy MJ