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U.S. Department of Health and Human Services

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Title:  Comparative pharmacokinetics and bioavailability of oxolinic acid in channel catifish (Ictalurus punctatus) and rainbow trout (Oncorhynchus mykiss).
 
Authors:  Kleinow KM, Jarboe HH, Shoemaker KE, Greenless KJ
 
Drug:  Oxolinic acid
 
Fish species:  Catfish, channel
 
Date:  1994
 
t1/2-hr:  70
 
Sample:  blood, plasma
 
Ave Weight (gm):  622
 
Ave Water temp (°C):  14
 
Water:  Freshwater
 
Dosage:  5 mg/kg sd
 
Route:  IV
 
Comments:  Fish had aortic catheters and indwelling stomach tubes. T1/2 alpha=0.68 h.
 
Cl:  0.009 L/kg/h
 
Vd:  0.88 L/kg
 
Citation:  Canadian J. Fisheries and Aquatic Sciences 51:1205-1211
 
Link:  http://md1.csa.com/partners/viewrecord.php?requester=gs&collection=ENV&recid=3621471  Opens a new window
 
Genus Species:  Ictalurus punctatus
 
Drug Class:  Antibiotic-Quinolone
 
t1/2-detail:  69.3 +/-6.9 h
 
Wt gm-detail:  622+/-127 g
 
Water temp (°C)-detail:  14 C
 
Dosage-detail:  5 mg/kg sd
 
Method:  HPLC
 
Authors-red:  Kleinow KM, Jarboe HH, Shoemaker KE, Greenless KJ
 
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