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Title:
Comparative pharmacokinetics and bioavailability of oxolinic acid in channel catifish (Ictalurus punctatus) and rainbow trout (Oncorhynchus mykiss).
Authors:
Kleinow KM, Jarboe HH, Shoemaker KE, Greenless KJ
Drug:
Oxolinic acid
Fish species:
Trout, rainbow
Date:
1994
t1/2-hr:
81
Sample:
blood, plasma
Ave Weight (gm):
798
Ave Water temp (°C):
14
Water:
Freshwater
Dosage:
5 mg/kg sd
Route:
IV
Comments:
Fish had aortic catheters and indwelling stomach tubes. T 1/2 alpha=0.15 h.
Cl:
0.017 L/kg/h
Vd:
1.817+/-0.219 L/kg
Citation:
Canadian J. Fisheries and Aquatic Sciences 51:1205-1211
Link:
http://md1.csa.com/partners/viewrecord.php?requester=gs&collection=ENV&recid=3621471
Genus Species:
Oncorhynchus mykiss
Drug Class:
Antibiotic-Quinolone
t1/2-detail:
81.3+/-22.5 h
Wt gm-detail:
798+/-222 g
Water temp (°C)-detail:
14 C
Dosage-detail:
5 mg/kg sd
Method:
HPLC
Authors-red:
Kleinow KM, Jarboe HH, Shoemaker KE, Greenless KJ
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