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Title:  Comparative pharmacokinetics and bioavailability of oxolinic acid in channel catifish (Ictalurus punctatus) and rainbow trout (Oncorhynchus mykiss).
Authors:  Kleinow KM, Jarboe HH, Shoemaker KE, Greenless KJ
Drug:  Oxolinic acid
Fish species:  Trout, rainbow
Date:  1994
t1/2-hr:  81
Sample:  blood, plasma
Ave Weight (gm):  798
Ave Water temp (°C):  14
Water:  Freshwater
Dosage:  5 mg/kg sd
Route:  IV
Comments:  Fish had aortic catheters and indwelling stomach tubes. T 1/2 alpha=0.15 h.
Cl:  0.017 L/kg/h
Vd:  1.817+/-0.219 L/kg
Citation:  Canadian J. Fisheries and Aquatic Sciences 51:1205-1211
Link:  http://md1.csa.com/partners/viewrecord.php?requester=gs&collection=ENV&recid=3621471  Opens a new window
Genus Species:  Oncorhynchus mykiss
Drug Class:  Antibiotic-Quinolone
t1/2-detail:  81.3+/-22.5 h
Wt gm-detail:  798+/-222 g
Water temp (°C)-detail:  14 C
Dosage-detail:  5 mg/kg sd
Method:  HPLC
Authors-red:  Kleinow KM, Jarboe HH, Shoemaker KE, Greenless KJ