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Title:
Pharmacokinetics of flumequine and in vitro activity against bacterial pathogens of gilthead sea bream Sparus aurata.
Authors:
Rigos G, Trypenou AE, Nengas I, Yiagnisis M, Koutsodimou M, Alexis M, Troisi GM
Drug:
Flumequine
Fish species:
Seabream, gilthead
Date:
2003
t1/2-hr:
30
Sample:
blood, plasma
Ave Weight (gm):
170
Ave Water temp (°C):
19
Water:
Saltwater
Dosage:
10 mg/kg sd
Route:
IV
Comments:
AUC 119.59 ug.hr/ml
Cl:
0.05 L/kg/h
Vc:
0.15 L/kg
Vd:
0.57 L/kg
Citation:
Diseases of Aquatic Organisms 54:35-41
Link:
http://www.int-res.com/articles/dao2003/54/d054p035.pdf
Genus Species:
Sparus aurata
Drug Class:
Antibiotic-Quinolone
t1/2-detail:
30 hr
Wt gm-detail:
170 g
Water temp (°C)-detail:
19+/-0.05 C
Dosage-detail:
10 mg/kg sd
Method:
HPLC
Authors-red:
Rigos G, Trypenou AE, Nengas I, Yiagnisis M, Koutsodimou M, Alexis M, Troisi GM
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