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Title:
Pharmacokinetics of flumequine and in vitro activity against bacterial pathogens of gilthead sea bream Sparus aurata.
Authors:
Rigos G, Trypenou AE, Nengas I, Yiagnisis M, Koutsodimou M, Alexis M, Troisi GM
Drug:
Flumequine
Fish species:
Seabream, gilthead
Date:
2003
t1/2-hr:
48
est:
est
Sample:
blood, plasma
Ave Weight (gm):
170
Ave Water temp (°C):
19
Water:
Saltwater
Dosage:
20 mg/kg sd
Route:
PO
Comments:
t 1/2 est from graph. AUC claculated 70.10ug.h/ml. Bioavailability 29%.
Citation:
Diseases of Aquatic Organisms 54:35-41
Link:
http://www.int-res.com/articles/dao2003/54/d054p035.pdf
Genus Species:
Sparus aurata
Drug Class:
Antibiotic-Quinolone
t1/2-detail:
48 hr est
Wt gm-detail:
170 g
Water temp (°C)-detail:
19+/-0.05 C
Dosage-detail:
20 mg/kg sd
Method:
HPLC
Authors-red:
Rigos G, Trypenou AE, Nengas I, Yiagnisis M, Koutsodimou M, Alexis M, Troisi GM
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