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U.S. Department of Health and Human Services

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Title:  Bioavailability and pharmacokinetics of a praziquantel bolus in kingfish Seriola lalandi.
 
Authors:  Tubbs L, Tingle M
 
Drug:  Praziquantel
 
Fish species:  Amberjack, yellowtail (kingfish)
 
Date:  2006
 
t1/2-hr:  7
 
Sample:  blood, plasma
 
Ave Weight (gm):  1500
 
Ave Water temp (°C):  19
 
Water:  Saltwater
 
Dosage:  40 mg/kg sd*
 
Route:  PO
 
Comments:  Oral intubation in DMSO solution, compare to in feed. Bioav 50.8%. All residues incr at 6h post dose (enterohepatic circ?).
 
Citation:  Diseases of Aquatic Organisms 69:233-238
 
Link:  http://www.int-res.com/abstracts/dao/v69/n2-3/p233-238/  Opens a new window
 
Genus Species:  Seriola lalandi
 
Drug Class:  Antiparasitic-Praziquantel
 
t1/2-detail:  6.57 h
 
Wt gm-detail:  1-2 kg
 
Water temp (°C)-detail:  18-19 C
 
Dosage-detail:  40 mg/kg sd*
 
Method:  HPLC
 
Authors-red:  Tubbs L, Tingle M.
 
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