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U.S. Department of Health and Human Services

PhishPharm - Detail

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Title:  Bioavailability and pharmacokinetics of a praziquantel bolus in kingfish Seriola lalandi.
Authors:  Tubbs L, Tingle M
Drug:  Praziquantel
Fish species:  Amberjack, yellowtail (kingfish)
Date:  2006
t1/2-hr:  9
Sample:  blood, plasma
Ave Weight (gm):  1500
Ave Water temp (°C):  19
Water:  Saltwater
Dosage:  40 mg/kg sd
Route:  IV
Comments:  T max= 0.5 h, Cmax=20 ug/ml, AUC = 178/24hr. Residues cleared below LOQ by 24 hr. All residues incr at 6h post dose (enterohepatic circ?).
Citation:  Diseases of Aquatic Organisms 69:233-238
Link:  http://www.int-res.com/abstracts/dao/v69/n2-3/p233-238/  Opens a new window
Genus Species:  Seriola lalandi
Drug Class:  Antiparasitic-Praziquantel
t1/2-detail:  8.57 h
Wt gm-detail:  1-2 kg
Water temp (°C)-detail:  18-19 C
Dosage-detail:  40 mg/kg sd
Method:  HPLC
Authors-red:  Tubbs L, Tingle M.