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U.S. Department of Health and Human Services

PhishPharm - Detail
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Title:  Temperature and congener structure affect the enantioselectivity of toxaphene elimination by fish.
 
Authors:  Maruya KA, Smalling KL, Vetter W
 
Drug:  Toxaphene
 
Fish species:  Mummichog
 
Date:  2005
 
t1/2-hr:  336
 
Sample:  whole body
 
Ave Water temp (°C):  15
 
Water:  Saltwater
 
Dosage:  naturally contmainated
 
Route:  NONE
 
Comments:  Salinity 32 ppt. Residue (ng/g) Enantiomers (E1, E2) E1: d0=760, d3=442, d11=176, d20=150, d64=120. E2: d0=460, d3=138, d11=24, d20=nd, d64=nd. K2=-0.05/d. More rapid depletion in warmer water.
 
Metabolites:  B6-923
 
Citation:  Environmental Science and Technology 39:3999-4004
 
Link:  http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15984775&query_hl=11  Opens a new window
 
Genus Species:  Fundulus heteroclitus heteroclitus
 
Drug Class:  Organic-Hydrocarbon
 
t1/2-detail:  14 d
 
Wt gm-detail:  adults
 
Water temp (°C)-detail:  15+/-2.8°C
 
Dosage-detail:  naturally contaminated
 
Method:  GC/EC-MS
 
Authors-red:  Maruya KA, Smalling KL, Vetter W
 
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