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U.S. Department of Health and Human Services

PhishPharm - Detail
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Title:  Total residue depletion and metabolic profile of selected drugs in salmonids: 17±-Methyltestosterone.
 
Authors:  Hayton WL (1997c)
 
Drug:  Methyltestosterone
 
Fish species:  Trout, rainbow
 
Date:  1997
 
t1/2-hr:  19
 
Sample:  blood, plasma
 
Ave Weight (gm):  427
 
Ave Water temp (°C):  12
 
Water:  Freshwater
 
Dosage:  37.6 µCi (.25 mg)
 
Route:  IVC
 
Comments:  Only one fish was used; Vd= 1.86 L/kg; Vc= 1.45 L/kg, log-linear= 18.7 h distribution= 2.5 h. Residues (ppb) 72 hr after IV dose = 14.9.
 
Cl:  0.39 L/kg/h
 
Vc:  1.45 L/kg
 
Vd:  1.86 L/kg
 
Citation:  Final FDA Report. Contract 223-93-7014. Vol 2.
 
Link:  none  Opens a new window
 
Genus Species:  Oncorhynchus mykiss
 
Drug Class:  Hormone-Testosterone
 
t1/2-detail:  log-linear= 18.7 hdistribution= 2.5 h
 
Wt gm-detail:  427 g
 
Water temp (°C)-detail:  12 C
 
Dosage-detail:  37.6 µCi (.25 mg)
 
Method:  HPLC-Rad
 
Authors-red:  Hayton WL (1997c)
 
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