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U.S. Department of Health and Human Services

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Title:  Comparative pharmacokinetics and bioavailability of oxytetracycline in giant tiger prawn.
 
Authors:  Sangrungruang K, Chotchuang A, Ueno R
 
Drug:  Oxytetracycline
 
Fish species:  Shrimp, giant tiger prawn (black tiger)
 
Date:  2004
 
t1/2-hr:  7
 
Sample:  blood, hemolymph
 
Ave Weight (gm):  24
 
Ave Water temp (°C):  30
 
Water:  Saltwater
 
Dosage:  10 mg/kg sd
 
Route:  PO
 
Comments:  Ka = 0.138 per hour, Ke = 0.1 per hour, Ta1/2 = 4.08 h, AUC = 455 ug/h/mL, MRT = 20 h. Tmax 9 hr. Bioavail 59.9%.
 
Vd:  14.3 L/kg
 
Citation:  Fisheries Science 70:467-472
 
Link:  http://dx.doi.org/10.1111/j.1444-2906.2004.00827.x  Opens a new window
 
Genus Species:  Penaeus monodon
 
Drug Class:  Antibiotic-Tetracycline
 
t1/2-detail:  6.93 h
 
Wt gm-detail:  23.6 g
 
Water temp (°C)-detail:  30 C
 
Dosage-detail:  10 mg/kg sd
 
Method:  HPLC
 
Authors-red:  Sangrungruang K, Chotchuang A, Ueno R
 
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