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U.S. Department of Health and Human Services

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Title:  Oxytetracycline residues in rainbow trout analysed by a rapid HPLC method.
 
Authors:  Nordlander I, Johnsson H, Osterdahl B
 
Drug:  Oxytetracycline
 
Fish species:  Trout, rainbow
 
t1/2-hr:  72
 
est:  est
 
Sample:  muscle
 
Ave Weight (gm):  424
 
Ave Water temp (°C):  7
 
Water:  Freshwater
 
Dosage:  75 mg/kg 10 d
 
Route:  PO
 
Comments:  Fish were naturally infected with Vibrio anguillarum, Residues mg/kg: day 6 = 0.77, day 10 = 0.30, day 13 = 0.11, day 23 = 0.041, day 32 = 0.021, day 41 = 0.021, day 60 = 0.011, day 82 = 0.016, Steady state reached at day 32. T1/2 estimated from mean concentrations to be between 4-7 days.
 
Citation:  Food Additives and Contaminants 4:291-296
 
Link:  http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&db=PubMed&list_uids=3653453&dopt=Abstract  Opens a new window
 
Genus Species:  Oncorhynchus mykiss
 
Drug Class:  Antibiotic-Tetracycline
 
Wt gm-detail:  310-501gm
 
Water temp (°C)-detail:  Dec during 82d - 12 C to 2 C
 
Dosage-detail:  75 mg/kg 10 d
 
Method:  HPLC
 
Authors-red:  Nordlander I, Johnsson H, Osterdahl B
 
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