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U.S. Department of Health and Human Services

PhishPharm - Detail
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Title:  Pharmacokinetics of sulphamonomethoxine in cultured yellowtail after oral administration.
 
Authors:  Ueno R, Uno K, Aoki T
 
Drug:  Sulfamonomethoxine
 
Fish species:  Amberjack, Japanese (yellowtail)
 
Date:  1994
 
t1/2-hr:  69
 
Sample:  liver
 
Ave Weight (gm):  357
 
Ave Water temp (°C):  22
 
Water:  Saltwater
 
Dosage:  400 mg/kg sd
 
Route:  PO
 
Comments:  T1/2 field=parent. No SMM detected 12d after administration. Residues 0.5h=83, 1h=107, 3h=106, 6h=41, 9h=20, 12h=13, 24h=1.6, 2d=0.3, 3d=0.2, 5d=0.3, 8d=0.2, 12 -20d nd ug/g. Glucuronide-SMM metabolite residues at Tmax (1h)=nd, at 20d=7.0 ug/g; Glucuronide-AcSMM metabolite residues at Tmax (1h)=nd, at 20d=2.3ug/g.
 
Metabolites:  N4-acetyl-Sulfamonomethoxine, glucronide conjugate
 
Citation:  Food Research International 27:33-37
 
Dep-time:  11.7d
 
Link:  http://dx.doi.org/10.1016/0963-9969(94)90175-9  Opens a new window
 
Genus Species:  Seriola quinqueradiata
 
Drug Class:  Antibiotic-Sulfa
 
t1/2-detail:  69.4 h=parent
 
Wt gm-detail:  357 g
 
Water temp (°C)-detail:  22 C
 
Dosage-detail:  400 mg/kg sd
 
Method:  HPLC
 
Authors-red:  Ueno R, Uno K, Aoki T
 
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