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Title:
Pharmacokinetics of sulphamonomethoxine in cultured yellowtail after oral administration.
Authors:
Ueno R, Uno K, Aoki T
Drug:
Sulfamonomethoxine
Fish species:
Amberjack, Japanese (yellowtail)
Date:
1994
t1/2-hr:
69
Sample:
liver
Ave Weight (gm):
357
Ave Water temp (°C):
22
Water:
Saltwater
Dosage:
400 mg/kg sd
Route:
PO
Comments:
T1/2 field=parent. No SMM detected 12d after administration. Residues 0.5h=83, 1h=107, 3h=106, 6h=41, 9h=20, 12h=13, 24h=1.6, 2d=0.3, 3d=0.2, 5d=0.3, 8d=0.2, 12 -20d nd ug/g. Glucuronide-SMM metabolite residues at Tmax (1h)=nd, at 20d=7.0 ug/g; Glucuronide-AcSMM metabolite residues at Tmax (1h)=nd, at 20d=2.3ug/g.
Metabolites:
N4-acetyl-Sulfamonomethoxine, glucronide conjugate
Citation:
Food Research International 27:33-37
Dep-time:
11.7d
Link:
http://dx.doi.org/10.1016/0963-9969(94)90175-9
Genus Species:
Seriola quinqueradiata
Drug Class:
Antibiotic-Sulfa
t1/2-detail:
69.4 h=parent
Wt gm-detail:
357 g
Water temp (°C)-detail:
22 C
Dosage-detail:
400 mg/kg sd
Method:
HPLC
Authors-red:
Ueno R, Uno K, Aoki T
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