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U.S. Department of Health and Human Services

PhishPharm - Detail

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Title:  In vivo microdialysis sampling of phenol and phenyl glucuronide in the blood of unanesthetized rainbow trout: implications for toxicokinetic studies.
 
Authors:  McKim Jr JM, McKim Sr JM, Naumann S, Hammermeister DE, Foffman AD, Klassen
 
Drug:  Phenol
 
Fish species:  Trout, rainbow
 
Date:  1993
 
t1/2-hr:  1
 
est:  est
 
Sample:  blood, plasma
 
Ave Weight (gm):  750
 
Ave Water temp (°C):  11
 
Water:  Freshwater
 
Dosage:  7 mg/L 180 min
 
Route:  BATH
 
Comments:  Microdialysis using dorsal aorta
 
Metabolites:  Phenyl glucuronide
 
Citation:  Fundamental and Applied Toxicology 20:190-198
 
Link:  http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=8449391&dopt=Abstract  Opens a new window
 
Genus Species:  Oncorhynchus mykiss
 
Drug Class:  Organic-Phenol
 
Wt gm-detail:  600-900 g
 
Water temp (°C)-detail:  11+/-1 C
 
Dosage-detail:  7 mg/L for 180 min
 
Method:  HPLC
 
Authors-red:  McKim Jr JM, McKim Sr JM, Naumann S, Hammermeister DE, Foffman AD, Klassen
 
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