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U.S. Department of Health and Human Services

PhishPharm - Detail
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Title:  Accumulation and loss of residues of 3-trifluoromethyl-4-nitrophenol (TFM) in fish muscle tissue : laboratory studies.
 
Authors:  Sills JB, Allen JL
 
Drug:  TFM-(3-Trifluoromethyl-4-nitrophenol)
 
Fish species:  Catfish, channel
 
Date:  1975
 
t1/2-hr:  8
 
est:  est
 
Sample:  muscle
 
Ave Weight (gm):  800
 
Ave Water temp (°C):  19
 
Water:  Freshwater
 
Dosage:  1 mg/l 12 hours
 
Route:  BATH
 
Comments:  Residues in all 8 species were near limit of detection (0.01 ug/g) within 24 hrs. High pH in water reduces absorption (seen with increased hardness-which also incr pH). Temperature had little effect on residue levels. Hardness = 20-22, pH - 7.1-7.6, - residues at Withdrawal time 0 h=1.67, 4 h=0.18, 8 h=0.06, 12 h = 0.02, 24 h=0.02.
 
Citation:  Investigations in Fish Control. U.S. Dept. of the Interior, Fish and Wildlife Service, Bureau of Sport Fisheries and Wildlife. SH157.7.I58 no.65
 
Dep-time:  near 24 h
 
Link:  none  Opens a new window
 
Genus Species:  Ictalurus punctatus
 
Drug Class:  Organic-Phenol
 
t1/2-detail:  < 8 h
 
Wt gm-detail:  400-1200 gm
 
Water temp (°C)-detail:  18.5 C
 
Dosage-detail:  1 mg/l 12 hrs
 
Method:  GC
 
Authors-red:  Sills JB, Allen JL
 
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