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U.S. Department of Health and Human Services

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Title:  Bioaccumulation potential of 4''-epi-(Methylamino)-4''-deoxyavermectin B1a Benzoate (Emamectin Benzoate) in Bluegill sunfish.
 
Authors:  Chukwudebe AC, Andrew N, Drottar K, Swigert J, Wislocki PG
 
Drug:  Emamectin Benzoate
 
Fish species:  Bluegill
 
Date:  1996
 
t1/2-hr:  91
 
est:  est
 
Sample:  muscle
 
Ave Weight (gm):  2
 
Ave Water temp (°C):  22
 
Water:  Freshwater
 
Dosage:  1.6 ug/l 28 d
 
Route:  BATH
 
Comments:  Steady state concentration not reached by 28 days. Residue levels on day 28=40 ug/kg. Emamectin Benzoate (3H). Equilbrium bioconc. Factor = 30, indicating unlikely to biomagnifiy in the food chain.
 
Metabolites:  N-demethylated derivative
 
Citation:  J. Agricultural and Food Chemistry 44:2894-2899
 
Dep-time:  .018/d dep rate constant (90% gone by d 13)
 
Link:  http://pubs.acs.org/cgi-bin/abstract.cgi/jafcau/1996/44/i09/abs/jf960228z.html  Opens a new window
 
Genus Species:  Lepomis macrochirus
 
Drug Class:  Antiparasitic-Avermectin
 
t1/2-detail:  3.8 days est by author
 
Wt gm-detail:  1.5+/-0.6 g
 
Water temp (°C)-detail:  22+/-1 C
 
Dosage-detail:  1.6 ug/l for 28 d
 
Method:  HPLC-Rad
 
Authors-red:  Chukwudebe AC, Andrew N, Drottar K, Swigert J, Wislocki PG
 
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