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U.S. Department of Health and Human Services

PhishPharm - Detail

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Title:  Residues of the lampricides 3-trifluoromethyl-4-nitrophenol and niclosamide in muscle tissue of rainbow trout.
 
Authors:  Hubert TD, Bernardy JA, Vue C, Dawson VK, Boogaard MA, Schreier TM, Gingerich WH
 
Drug:  Niclosamide-(2,5-Dichloro-4-nitrosalicylanilide)
 
Fish species:  Trout, rainbow
 
Date:  2005
 
Sample:  muscle+skin
 
Ave Weight (gm):  300
 
Ave Water temp (°C):  12
 
Water:  Freshwater
 
Dosage:  0.055 mg/l 24 h
 
Route:  BATH
 
Comments:  Residues: (14C)Niclosamide 1.4, niclosamide-glu 0.0644, niclosamide sulfate ester 1.2 nmol/g. Mean terminal radioactive residues at end of exposure 3.33 nmol/g.
 
Metabolites:  Glucuronide, sulfate ester
 
Citation:  J. Agricultural Food Chemistry 53:5342-5346
 
Link:  http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15969516&query_hl=1  Opens a new window
 
Genus Species:  Oncorhynchus mykiss
 
Drug Class:  Antiparasitic-Niclosamide
 
Wt gm-detail:  300 g
 
Water temp (°C)-detail:  12+/-1°C
 
Dosage-detail:  0.055 mg/l 24 h
 
Method:  HPLC-Rad
 
Authors-red:  Hubert TD, Bernardy JA, Vue C, Dawson VK, Boogaard MA, Schreier TM, Gingerich WH
 
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