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Title:
Pharmacokinetic studies of florfenicol in Koi carp and Threespot gourami Trichogaster trichopterus after oral and intramuscular treatment
Authors:
Yanong RPE, Curtis EW, Simmons R, Bhattaram VA, Gopalakrishnan M, Ketabi N, Nagaraja NV, Derendorf H
Drug:
Florfenicol
Fish species:
Gourami, three spot
Date:
2005
t1/2-hr:
4
Sample:
blood, plasma
Ave Weight (gm):
19
Ave Water temp (°C):
24
Water:
Freshwater
Dosage:
50 mg/kg sd
Route:
IM
Comments:
Ka absorption = 6h. Non compartmental analysis C max=28 h, Tmax=3 h, AUC=188.6 ug/h//ml, t1/2=4.8 h.
Cl:
0.3 L/kg/h
Vd:
2.0 L/kg
Citation:
J. Aquatic Animal Health 17:129-137
Link:
http://afs.allenpress.com/perlserv/?request=get-abstract&doi=10.1577%2FH03-065.1
Genus Species:
Trichopodus trichopterus
Drug Class:
Antibiotic-Phenicol
t1/2-detail:
4.2
Wt gm-detail:
19+/-3 g
Water temp (°C)-detail:
23-25 C
Dosage-detail:
50 mg/kg sd
Method:
HPLC
Authors-red:
Yanong RPE, Curtis EW, Simmons R, Bhattaram VA, Gopalakrishnan M, Ketabi N, Nagaraja NV, Derendorf H
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