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Title:
High-performance liquid chromatographic analysis of Romet-30 in Chinook salmon (Oncorhynchus tshawytscha): wash-out time, tissue distribution in muscle, liver, and skin, and metabolism of sulphadimethoxine.
Authors:
Zheng M, Liu H, Hall SF, Kitts DD, McErlane KM
Drug:
Sulfadimethoxine
Fish species:
Salmon, chinook
Date:
1994
t1/2-hr:
96
est:
est
Sample:
liver
Ave Weight (gm):
1094
Ave Water temp (°C):
9
Water:
Saltwater
Dosage:
40 mg/kg 10 d
Route:
PO
Comments:
Metabolite - N4-Ac-SDM - t1/2 estimated from graph.
Metabolites:
N4-A-SDM
Citation:
J. Chromatography 670:77-88
Dep-time:
> 20 d
Link:
http://dx.doi.org/10.1016/0021-9673(94)80282-3
Genus Species:
Oncorhynchus tshawytscha
Drug Class:
Antibiotic-Sulfa
t1/2-detail:
< 4 d
Wt gm-detail:
615-1800 g
Water temp (°C)-detail:
8-9 C
Dosage-detail:
40 mg/kg for 10 d
Method:
HPLC
Authors-red:
Zheng M, Liu H, Hall SF, Kitts DD, McErlane KM
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