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U.S. Department of Health and Human Services

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Title:  Absorption and Excretion of Cefquinome in Coho Salmon (Oncorhynchus kisutch) in Freshwater at 10°C
 
Authors:  San Martin BN, Bataglia J, Hernandez P, Quiroz A, Canon H
 
Drug:  Cefquinome
 
Fish species:  Salmon, coho
 
Date:  1998
 
t1/2-hr:  9
 
Sample:  brain
 
Ave Weight (gm):  100
 
Ave Water temp (°C):  10
 
Water:  Freshwater
 
Dosage:  20 mg/kg sd
 
Route:  IP
 
Comments:  Fish were anaesthetized prior to dosing with 1 mg/l MS-222. Cmax=2.18 ug/g. Tmax=6h. AUC= 50.087. Residues 0.5h=0.5, 2h=0.4, 6h=2.2, 12h=1.6, 24h=1.2, 48h=0.1. Withdrawl time based on 99.9% elimination.
 
Citation:  J. Vet. Med. A 45,615-635
 
Dep-time:  69 h
 
Link:  http://www.ncbi.nlm.nih.gov/pubmed/9923144  Opens a new window
 
Genus Species:  Oncorhynchus kisutch
 
Drug Class:  Antibiotic-Cephalosporin
 
t1/2-detail:  9.35
 
Wt gm-detail:  100 +/- 5
 
Water temp (°C)-detail:  10 +/- 0.3 C
 
Dosage-detail:  0.8 ug/L Cobactan (R )corresponding to 20 mg/kg - SD
 
Method:  Micro
 
Authors-red:  San Martin BN, Bataglia J, Hernandez P, Quiroz A, Canon H
 
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