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U.S. Department of Health and Human Services

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Title:  Pharmacokinetic and depletion studies of sarafloxacin after oral administration to eel (Anguilla anguilla).
 
Authors:  Ho S-P, Cheng C-F, Wang W-S
 
Drug:  Sarafloxacin
 
Fish species:  Eel, European
 
Date:  1999
 
t1/2-hr:  50
 
est:  est
 
Sample:  muscle
 
Ave Weight (gm):  146
 
Ave Water temp (°C):  24
 
Water:  Freshwater
 
Dosage:  15 mg/kg sd
 
Route:  PO
 
Comments:  Cmax=1.18 ug/g at 24 h (listed as 1.92 in abstract). Sarafloxacin fell below detectable limits after 7d.
 
Citation:  J. Veterinary Medical Science 61:5:459-463
 
Dep-time:  7d
 
Link:  http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=10379934  Opens a new window
 
Genus Species:  Anguilla anguilla
 
Drug Class:  Antibiotic-Quinolone
 
t1/2-detail:  50 est
 
Wt gm-detail:  146+/-3 g
 
Water temp (°C)-detail:  24+/-0.7 C
 
Dosage-detail:  15 mg/kg sd
 
Method:  HPLC
 
Authors-red:  Ho S-P, Cheng C-F, Wang W-S
 
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