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U.S. Department of Health and Human Services

PhishPharm - Detail

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Title:  Comparative pharmacokinetics of oxytetracycline in rainbow trout (Salmo gairdneri) and African catfish (Clarias gariepinus).
 
Authors:  Grondel JL, Nouws JFM, Schutte AR, Driessens F
 
Drug:  Oxytetracycline
 
Fish species:  Catfish, North African
 
Date:  1989
 
t1/2-hr:  80
 
Sample:  blood, plasma
 
Ave Weight (gm):  293
 
Ave Water temp (°C):  25
 
Water:  Freshwater
 
Dosage:  60 mg/kg sd
 
Route:  IV
 
Comments:  AUC = 5369+/- 1102 ug h/ml. T 1/2 alpha = 5.2 h, beta 80.3. Cl, Vc, and Vd were calculated in a model-independent way according to Baggot (1977).
 
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